ABAP Profiling gives a holistic view of execution with the overview. It also provides Hit List, Call-sequence, Call-timelines, and DB accesses information. Analysing information provided by Profiling helps to understand Performance Bottlenecks. ABAP Profiling in Eclipse is equivalent to old SE30 or SAT transactions in SAP GUI. SAP dedicated a separate perspective for ABAP Profiling.
Eclipse preferences are easy way to access and change configurations, look and feel of Eclipse.